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Year Number of Results
2005 1
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36 results

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Page 1
Chlorogenic acid suppresses miR-460a in the regulation of Bcl-2, causing interleukin-1beta reduction in thiram exposed chondrocytes via caspase-3/caspase-7 pathway.
Kulyar MF, Mo Q, Yao W, Ding Y, Yan Z, Du H, Pan H, Li K, Gao J, Shahzad M, Mansoor MK, Iqbal M, Waqas M, Akhtar M, Bhutta ZA, Li J. Kulyar MF, et al. Phytomedicine. 2022 Sep;104:154296. doi: 10.1016/j.phymed.2022.154296. Epub 2022 Jul 2. Phytomedicine. 2022. PMID: 35809377
RESULTS: The CGA decreased the apoptosis rate with the deactivation of miR-460a, accompanied by the activation of Bcl-2. The high expression of miR-460a reduced the cell viability of chondrocytes in vitro and in vivo, that led to the interleukin-1beta production. Wh …
RESULTS: The CGA decreased the apoptosis rate with the deactivation of miR-460a, accompanied by the activation of Bcl-2. The high exp …
NFκB signaling in alveolar rhabdomyosarcoma.
Cleary MM, Mansoor A, Settelmeyer T, Ijiri Y, Ladner KJ, Svalina MN, Rubin BP, Guttridge DC, Keller C. Cleary MM, et al. Dis Model Mech. 2017 Sep 1;10(9):1109-1115. doi: 10.1242/dmm.030882. Dis Model Mech. 2017. PMID: 28883017 Free PMC article.
Alveolar rhabdomyosarcoma (aRMS) is a pediatric soft tissue cancer commonly associated with a chromosomal translocation that leads to the expression of a Pax3:Foxo1 or Pax7:Foxo1 fusion protein, the developmental underpinnings of which may give clues to its therapeutic approaches …
Alveolar rhabdomyosarcoma (aRMS) is a pediatric soft tissue cancer commonly associated with a chromosomal translocation that leads to the ex …
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma.
Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Ishikawa Y, Zientek K, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Rudek MA, Xu L, Anders NM, Pal R, Harrold AP, Davies AM, Ashok A, Bushby D, Mancini M, Noakes C, Goodwin NC, Ordentlich P, Keck J, Hawkins DS, Rudzinski ER, Chatterjee B, Bächinger HP, Barr FG, Liddle J, Garcia BA, Mansoor A, Perkins TJ, Vakoc CR, Michalek JE, Keller C. Bharathy N, et al. Sci Signal. 2018 Nov 20;11(557):eaau7632. doi: 10.1126/scisignal.aau7632. Sci Signal. 2018. PMID: 30459282 Free PMC article.
HDAC3 inhibition by entinostat decreased the activity of the chromatin remodeling enzyme SMARCA4, which, in turn, derepressed the microRNA miR-27a. This reexpression of miR-27a led to PAX3:FOXO1 mRNA destabilization and chemotherapy sensitization in aRMS cells in cu …
HDAC3 inhibition by entinostat decreased the activity of the chromatin remodeling enzyme SMARCA4, which, in turn, derepressed the microRNA …
Potential risk assessment of miR-143 gene polymorphisms rs41291957 and rs353292 in colorectal cancer.
Ahmed MN, Mansoor Q, Baig RM, Tahir T, Abbasi SA. Ahmed MN, et al. Cell Mol Biol (Noisy-le-grand). 2020 Oct 31;66(7):169-173. Cell Mol Biol (Noisy-le-grand). 2020. PMID: 33287937
Excitingly, discovery of non-coding RNAs is considered to be a milestone in molecular oncology and emerging evidence is deepening our understanding about pivotal role of miRNAs in carcinogenesis. miR-143 has been experimentally verified to play an instrumental role as tumo …
Excitingly, discovery of non-coding RNAs is considered to be a milestone in molecular oncology and emerging evidence is deepening our unders …
Regulatory role of miR-125a expression with respect to its target genes LIFR, ERBB2 and STAT3 in the pathogenesis of recurrent pregnancy losses.
Manzoor U, Pandith AA, Amin I, Wani S, Baba SM, Wani UM, Mansoor S, Aein QU, Anwar I, Bahar B, Koul AM, Sanadhya D, Ahmad A. Manzoor U, et al. Int J Gynaecol Obstet. 2024 Mar 25. doi: 10.1002/ijgo.15496. Online ahead of print. Int J Gynaecol Obstet. 2024. PMID: 38528801

Furthermore, expression analysis of ERBB2 gene with respect to its regulatory miR-125a cases depicted a significant association (P = 0.0005). ...Also, decreased expression of miR-125a significantly conferred >2-fold increased risk for RPL (HR = 2.34: P < 0.05)

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Furthermore, expression analysis of ERBB2 gene with respect to its regulatory miR-125a cases depicted a significant association (P = …
36 results